Quantitative MRI Dixon signal drop and fat fraction for differentiating bone marrow lesions: a two-center prospective analysis
Quantitative Dixon MRI thresholds of %drop ≤ 19.8% and %fat ≤ 18.3% were established as reliable predictors of malignancy in bone marrow lesions. Dixon metrics demonstrated superior diagnostic accuracy (86.6-87.2%), compared to conventional T1-weighted sequences (79.2%). Excellent inter-reader reliability (κ = 0.895-0.943) supports the reproducibility of quantitative Dixon MRI in clinical practice.
Authors
- Maha Ibrahim Metwally (ORCID: https://orcid.org/0000-0002-4104-9738)
- Yassir Edrees Almalki (ORCID: https://orcid.org/0000-0001-7046-5311)
- Moosa Khalil
- Shimaa Abdelmoneem (ORCID: https://orcid.org/0000-0002-4076-1491)
- Sharifa Khalid Alduraibi (ORCID: https://orcid.org/0000-0003-0810-9337)
- hazem tantawy
- Mohamed G. Hamed (ORCID: https://orcid.org/0000-0002-5543-1604)
- Ahmed Mohamed Alsowey
- Mohammad Abd Alkhalik Basha (ORCID: https://orcid.org/0000-0002-9075-8020)
- Ziyad Almushayti (ORCID: https://orcid.org/0000-0001-8383-1624)
- Ahmed M. Abdelkhalik Basha
- Shaker Alshehri (ORCID: https://orcid.org/0000-0002-3285-6052)
Institutions
- Cairo University (EG)
- Qassim University (SA)
- Zagazig University (EG)
- McMaster University Medical Centre (CA)
- Najran University (SA)
- King Khalid University (SA)
- McMaster University (CA)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1186/s41747-025-00615-9
- Citations
- 1
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Zagazig University