Combination therapy does not decrease 30-day mortality but increases antibiotic consumption in methicillin-sensitive <i>S. aureus</i> bacteraemia
Our findings indicate that combination therapy does not confer a survival benefit over monotherapy in patients with MSSA bacteraemia. However, combination therapy was associated with a significant increase in antibiotic consumption. Therefore, our results do not support the routine use of combination therapy for MSSA bacteraemia in this patient population.
Authors
- Özge Özgen Top (ORCID: https://orcid.org/0000-0003-1468-4960)
- Murat Dizbay
- Elif Ayça Şahin (ORCID: https://orcid.org/0000-0002-2215-2756)
- Zeynep Tekin-Taş (ORCID: https://orcid.org/0000-0001-7232-8863)
- Hamid Habibi (ORCID: https://orcid.org/0000-0003-3981-2850)
- Hasan Selçuk Özger (ORCID: https://orcid.org/0000-0003-3894-0092)
- Pınar Aysert Yıldız
- İbrahim Orhun Hatipoğlu (ORCID: https://orcid.org/0009-0002-1344-9686)
Institutions
- Koç University (TR)
- Gazi Hastanesi (TR)
- Infectious Clinical Hospital No. 1 (RU)
- Gazi University (TR)
Publication Details
- Journal
- Journal of Chemotherapy
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1080/1120009x.2025.2556578
- Citations
- 1
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 1.32