Polyomavirus Antibodies for Merkel Cell Carcinoma Recurrence Detection

In this prospective cohort study, given a negative predictive value of 99.3%, a falling or negative titer may obviate the need for imaging, reducing radiation and contrast dye exposure. Conversely, a rising antibody titer should trigger closer follow-up, as it may lead to earlier detection of clinical recurrence and initiation of therapy.

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Publication Details

Journal
JAMA Dermatology
Published
2025-09-10
DOI
https://doi.org/10.1001/jamadermatol.2025.3155
Citations
2
Primary Topic
Polyomavirus and related diseases
Type
article
Field-Weighted Citation Impact
2.09
Controls
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article

Polyomavirus Antibodies for Merkel Cell Carcinoma Recurrence Detection

Tomoko Akaike, Kristina Lachance, Coley Doolittle‐Amieva, Kelsey Cahill et al.
2 citations
JAMA Dermatology
Polyomavirus and related diseases
2.09
article

Polyomavirus Antibodies for Merkel Cell Carcinoma Recurrence Detection

Tomoko Akaike, Kristina Lachance, Coley Doolittle‐Amieva, Kelsey Cahill, Daniel S. Hippe, Song Youn Park, Alex Z. Fu, Lindsay Gunnell, Paul Nghiem
article en
2 citations

Abstract

In this prospective cohort study, given a negative predictive value of 99.3%, a falling or negative titer may obviate the need for imaging, reducing radiation and contrast dye exposure. Conversely, a rising antibody titer should trigger closer follow-up, as it may lead to earlier detection of clinical recurrence and initiation of therapy.

JAMA DermatologyVol. 161(11)
University of Washington (US), Fred Hutch Cancer Center (US)
Openalex Percentile: Top 10%
Polyomavirus and related diseases
2.09
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