BOLD Long-Range Temporal Correlations Reflect Changes in Language and Depression Across Intensive Aphasia Therapy
LRTC changes across therapy reflect changes in both language performance and depression in chronic poststroke aphasia. Predominantly right perisylvian and domain-general regions seem critical for neuroplasticity in language rehabilitation. In addition, the observed role of right perisylvian regions in mood regulation highlights the interconnection of cognitive recovery and emotional well-being. LRTC may represent a valuable biomarker for tracking therapy-related neuroplasticity.
Authors
- Felix R. Dreyer (ORCID: https://orcid.org/0000-0003-1560-8126)
- Vadim V. Nikulin (ORCID: https://orcid.org/0000-0001-6082-3859)
- Friedemann Pulvermüller (ORCID: https://orcid.org/0000-0003-3210-7112)
- Anna‐Thekla Jäger (ORCID: https://orcid.org/0000-0002-3381-8453)
- Bettina Mohr
- Christopher J. Steele (ORCID: https://orcid.org/0000-0003-1656-7928)
- Milena R. Osterloh (ORCID: https://orcid.org/0009-0007-9616-1077)
- Anna Sadlon
Institutions
- Bielefeld University (DE)
- Humboldt-Universität zu Berlin (DE)
- Max Planck Institute for Human Cognitive and Brain Sciences (DE)
- Concordia University (US)
- Einstein Center for Neurosciences Berlin (DE)
- Berlin Center for Epidemiology and Health Research (DE)
- Cluster of Excellence "Matters of Activity. Image Space Material" (DE)
- Concordia University (CA)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Stroke
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1161/strokeaha.124.050064
- Primary Topic
- Neurobiology of Language and Bilingualism
- Type
- article
- Field-Weighted Citation Impact
- 0.00