Timing of Death in Children Referred for Intensive Care With Sepsis: Comparison of Two Cohorts in the United Kingdom, 2005–2011 vs. 2018–2023
In 2018-2023, the proportion of referrals for PICU retrieval with a clinical diagnosis of "sepsis" was low at 3%. As with our 2005-2011 cohort, most deaths occurred within 24 hours of first referral. Therefore, early recognition and resuscitation still have the greatest potential for improving sepsis outcomes, which has implications for clinical trials.
Authors
- Padmanabhan Ramnarayan (ORCID: https://orcid.org/0000-0003-0784-8154)
- Maik Honsel
- Mark Peters (ORCID: https://orcid.org/0000-0003-3653-4808)
- Elise Randle
- Maile Wedgwood
Institutions
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Institute of Infection and Immunity (CA)
- University College London (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Pediatric Critical Care Medicine
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1097/pcc.0000000000003825
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35