Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of <b>β</b> -catenin
This study uncovers a novel anti-LCSC mechanism of AC, offers alternative strategies for NSCLC treatment, and provides innovative lead compounds for the development of drugs targeting lung cancer stem cells.
Authors
- Wenying Yan (ORCID: https://orcid.org/0000-0001-5016-575X)
- Guoqiang Liu (ORCID: https://orcid.org/0000-0002-9754-587X)
- Hao Xie (ORCID: https://orcid.org/0000-0001-8077-9365)
- Linli Li (ORCID: https://orcid.org/0000-0001-7743-434X)
- Qian Li (ORCID: https://orcid.org/0009-0004-7052-8617)
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1093/jpp/rgaf081
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00