Matrine alleviates the immune imbalance of atopic dermatitis by up-regulating FOXO4 to inactivate circTNFRSF21-mediated JAK/STAT3 axis

MT alleviates the inflammatory response of atopic dermatitis by suppressing circTNFRSF21 expression to decrease the activity of STAT3 signaling pathway.

Authors

Haizhen Wang (ORCID: https://orcid.org/0000-0001-8135-4297)
Yi Pan (ORCID: https://orcid.org/0000-0002-5742-3202)
Meijunzi Luo (ORCID: https://orcid.org/0000-0003-0643-112X)
Pan Huang (ORCID: https://orcid.org/0000-0002-5927-0369)
Chang Wang (ORCID: https://orcid.org/0009-0005-1630-9453)
Rong Zhou

Institutions

Hunan University of Traditional Chinese Medicine (CN)
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)

Publication Details

Journal: Immunopharmacology and Immunotoxicology
Published: 2025-09-03
DOI: https://doi.org/10.1080/08923973.2025.2554662
Citations: 2
Primary Topic: Inflammasome and immune disorders
Type: article
Field-Weighted Citation Impact: 1.61

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article

Matrine alleviates the immune imbalance of atopic dermatitis by up-regulating FOXO4 to inactivate circTNFRSF21-mediated JAK/STAT3 axis

Haizhen Wang, Yi Pan, Meijunzi Luo, Pan Huang et al.

Sep 3, 2025

2 citations

Immunopharmacology and Immunotoxicology

Inflammasome and immune disorders

1.61

article

Matrine alleviates the immune imbalance of atopic dermatitis by up-regulating FOXO4 to inactivate circTNFRSF21-mediated JAK/STAT3 axis

Haizhen Wang, Yi Pan, Meijunzi Luo, Pan Huang, Chang Wang, Rong Zhou

September 3, 2025article en

2 citations

Abstract

MT alleviates the inflammatory response of atopic dermatitis by suppressing circTNFRSF21 expression to decrease the activity of STAT3 signaling pathway.

Immunopharmacology and ImmunotoxicologyVol. 47(5)

Hunan University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN), Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)

Openalex Percentile: Top 15%

Inflammasome and immune disorders

1.61

DOI Source OpenAlex

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Matrine alleviates the immune imbalance of atopic dermatitis by up-regulating FOXO4 to inactivate circTNFRSF21-mediated JAK/STAT3 axis — Haizhen Wang, Yi Pan, et al. · Immunopharmacology and Immunotoxicology (2025) | TGRS Research Map | TGRS