Radiation Therapy for Solitary Fibrous Tumor of the Orbit
Solitary fibrous tumor, formerly also referred to as hemangiopericytoma, is a fibroblastic mesenchymal neoplasm of the orbit that rarely metastasizes but has a propensity for local recurrence. The authors describe 5 cases of orbital solitary fibrous tumors that were treated with radiation. In 3 patients, radiation therapy was given in the neoadjuvant setting prior to surgery. In the remaining 2 patients, radiation was used palliatively in patients who declined surgery. In 4 of 5 cases, a measurable reduction in the size of the orbital mass was observed in response to radiation therapy; however, long-term adverse effects of radiation may not yet be evident, given the relatively short follow-up period for some of the patients in this report.
Authors
- Geoffrey E. Rose (ORCID: https://orcid.org/0000-0002-5364-7743)
- Tracy Lu
- Agni Kakouri (ORCID: https://orcid.org/0000-0002-1081-2948)
- B. Ashleigh Guadagnolo (ORCID: https://orcid.org/0000-0002-4489-7070)
- Matthew Debnam
- Kaveh Vahdani (ORCID: https://orcid.org/0000-0001-9764-474X)
- David H. Verity (ORCID: https://orcid.org/0000-0001-6982-6896)
- Bita Esmaeli (ORCID: https://orcid.org/0000-0002-3667-1821)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Moorfields Eye Hospital (GB)
- The University of Texas Health Science Center (US)
- University College London (GB)
Publication Details
- Journal
- Ophthalmic Plastic and Reconstructive Surgery
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1097/iop.0000000000003023
- Citations
- 1
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 1.67