Unraveling the Pertussis Outbreak in Mexico: Insights from a Multicenter 2024–2025 Study
We analyzed 59 pediatric pertussis cases during Mexico's 2024-2025 outbreak. Mortality was 13.6%, with low maternal Tdap coverage (27.1%) and incomplete infant vaccination (16.9%). Mortality correlated with intensive care unit admission, intubation, leukocytosis and coronavirus codetection. Peak leukocyte count predicted mortality ( P = 0.027; area under the curve = 0.79). Findings underscore the need for maternal immunization and early detection.
Authors
- Daniela Cisneros Saldaña (ORCID: https://orcid.org/0000-0002-7001-821X)
- Carlos Alfonso Builes Barrera (ORCID: https://orcid.org/0000-0001-6217-117X)
- María Elena Martínez Bustamante
- Ranferi Aragón Nogales
- María Citlalli Casillas Casillas
- Marisol Silva Dirzo
- L.P. Rivera (ORCID: https://orcid.org/0000-0001-6373-654X)
- José Iván Castillo Bejarano (ORCID: https://orcid.org/0000-0003-4270-2687)
- E. Garcia
- Ana Jocelyn Carmona Vargas
- Eduardo Arias de la Garza
- Victoria Jimenez Martinez (ORCID: https://orcid.org/0009-0005-2372-4989)
- Yolotl Hilario Sánchez Carrillo
Institutions
- Autonomous University of Chihuahua (MX)
- Universidad Autónoma de Nuevo León (MX)
- Instituto Tecnológico de Oaxaca (MX)
- Autonomous University of Campeche (MX)
- Centro Médico Nacional La Raza (MX)
- Hospital Fernández (AR)
- Hospital Angeles Clinica Londres (MX)
- Hospital Español (MX)
- Hospital Universitario Dr José Eleuterio Gonzalez (MX)
- Hospital Pediátrico Moctezuma (MX)
- Hospital del Niño (PA)
- Fundar (MX)
- University of Monterrey (MX)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1097/inf.0000000000004986
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00