Identifying ARRB2 as a Prognostic Biomarker and Key Player in the Tumor Microenvironment of Pancreatic Cancer through scPagwas Methodology
Macrophages, along with ARRB2, serve an essential function in the progression of PAAD and immune regulation. The identification of ARRB2 as a prognostic biomarker and its involvement in critical oncogenic pathways furnish a theoretical foundation for targeted therapeutic interventions. These discoveries contribute to the ongoing exploration of diagnostic, prognostic, and treatment strategies for PAAD.
Authors
- Yuchen Xia (ORCID: https://orcid.org/0000-0001-8460-3893)
- Kaidong Wang (ORCID: https://orcid.org/0000-0001-5196-9346)
- Xiangjun Fan (ORCID: https://orcid.org/0000-0001-5303-3488)
- Y. Wang
- Shiqi Ren
- Geng Tian (ORCID: https://orcid.org/0000-0001-5752-4436)
- Yang Li (ORCID: https://orcid.org/0000-0001-6675-2481)
- Chang Che
- Pengcheng Zhou (ORCID: https://orcid.org/0000-0003-1477-0586)
- Kailai Li (ORCID: https://orcid.org/0000-0002-2368-3217)
- Kun Zhang (ORCID: https://orcid.org/0000-0001-5675-8046)
- Chengcheng Liu (ORCID: https://orcid.org/0000-0003-0113-2673)
- Lei Wang (ORCID: https://orcid.org/0000-0002-6155-6892)
- Guanyi Lu (ORCID: https://orcid.org/0000-0002-3064-0768)
Institutions
- Central South University (CN)
- Nantong University (CN)
- Soochow University (CN)
- Affiliated Hospital of Nantong University (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Zhujiang Hospital (CN)
- Wuxi Ninth People's Hospital (CN)
- Zhuzhou Central Hospital (CN)
- Shandong First Medical University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Current Gene Therapy
- Published
- 2025-09-10
- DOI
- https://doi.org/10.2174/0115665232427614250904061700
- Citations
- 5
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 5.23