Indication for biologics in a real-world cohort of dupilumab treated chronic rhinosinusitis with nasal polyps patients according to international recommendations: evidence from the European CRS Outcome Registry (CHRINOSOR)
Real-world management of CRSwNP with biologics does not strictly follow the indication criteria established by international recommendations but depends on management criteria established by local authorities. These vary significantly and are either more or less stringent from one country to another. Dupilumab effectiveness in CRSwNP, whether these criteria are met or not, suggests that a broader CRSwNP population may benefit from dupilumab.
Authors
- Sven Schneider (ORCID: https://orcid.org/0000-0001-6438-1971)
- M Wagenmann
- Laura Van Gerven (ORCID: https://orcid.org/0000-0002-5325-7956)
- Anu Laulajainen‐Hongisto (ORCID: https://orcid.org/0000-0001-5109-6944)
- Andrea Ciofalo (ORCID: https://orcid.org/0000-0003-1468-459X)
- Sven Seys (ORCID: https://orcid.org/0000-0002-4399-9892)
- Peter W. Hellings (ORCID: https://orcid.org/0000-0001-6898-688X)
- Marco de Vincentiis (ORCID: https://orcid.org/0000-0002-1990-7820)
- Zuzana Diamant (ORCID: https://orcid.org/0000-0003-0133-0100)
- Simonetta Masieri (ORCID: https://orcid.org/0000-0003-0423-9505)
- Peter Valentin Tomazic (ORCID: https://orcid.org/0000-0001-6445-4800)
- Clemens Holzmeister (ORCID: https://orcid.org/0000-0003-2835-5121)
- Jens Kjeldsen (ORCID: https://orcid.org/0000-0001-8148-6572)
- Claus Bachert (ORCID: https://orcid.org/0000-0003-4742-1665)
- Isam Alobid (ORCID: https://orcid.org/0000-0001-7204-5599)
- Godelieve Mariën
- Sietze Reitsma (ORCID: https://orcid.org/0000-0003-1734-2632)
- Carlo Cavaliere (ORCID: https://orcid.org/0000-0002-0378-8935)
- Kathrin Scheckenbach (ORCID: https://orcid.org/0000-0002-2899-4487)
- G. Mortuaire (ORCID: https://orcid.org/0000-0002-1592-1625)
- Julia Eckl‐Dorna (ORCID: https://orcid.org/0000-0001-5981-1607)
- Josje Otten (ORCID: https://orcid.org/0009-0003-5437-3005)
- Alexandros Andrianakis (ORCID: https://orcid.org/0000-0002-2530-9931)
- C Hopkins
- Valérie Hox (ORCID: https://orcid.org/0000-0003-2390-294X)
- Valerie Lund
- A Tu (ORCID: https://orcid.org/0000-0003-2686-6390)
- W J Fokkens
- Giulia Bettio
- Joost de Kinderen
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- University of Helsinki (FI)
- Sun Yat-sen University (CN)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Medical University of Graz (AT)
- Charles University (CZ)
- Universitair Ziekenhuis Leuven (BE)
- Helsinki University Hospital (FI)
- Odense University Hospital (DK)
- Vienna General Hospital (AT)
- Centre Hospitalier Universitaire de Lille (FR)
- University Hospital Münster (DE)
- Hospital Clínic de Barcelona (ES)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Royal National Throat Nose and Ear Hospital (GB)
- Thomayer University Hospital (CZ)
- Hôpital Claude Huriez (FR)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Medical University of Vienna (AT)
- Sapienza University of Rome (IT)
- KU Leuven (BE)
Publication Details
- Journal
- Rhinology Journal
- Published
- 2025-01-09
- DOI
- https://doi.org/10.4193/rhin25.157
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00