Peroxisome proliferator-activated receptor pathway and key genes in cerebellar dysfunction induced by chronic intermittent alcohol exposure: a transcriptomic study
The PPAR pathway and four target genes (Bloc1s6, Gsk3b, Ppard, and Napb) may contribute to cerebellar dysfunction and increased alcohol preference induced by chronic alcohol exposure. These findings could help identify potential therapeutic targets for chronic alcohol exposure and alcohol preference and support further investigation into the underlying mechanisms involved.
Authors
- Xiaofeng Zhu (ORCID: https://orcid.org/0000-0003-0037-411X)
- Xunzhong Qi (ORCID: https://orcid.org/0000-0002-0619-2926)
- Lingyi Kong (ORCID: https://orcid.org/0000-0001-5519-1703)
- Jin Guo
- Wei Pan (ORCID: https://orcid.org/0000-0001-7353-3498)
- Guangtao Sun
- Yifan Zheng (ORCID: https://orcid.org/0000-0002-5320-0095)
- Shuang Wei (ORCID: https://orcid.org/0000-0002-6250-6926)
Institutions
- Jiamusi University (CN)
- Mudanjiang Medical University (CN)
- First Affiliated Hospital of Jiamusi University (CN)
Publication Details
- Journal
- Neurological Research
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1080/01616412.2025.2556244
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00