Relation of Visual Function, Retinal Thickness by Optical Coherence Tomography, and MRI Brain Volume in Pediatric-Onset Multiple Sclerosis
Our results demonstrate that changes in visual pathway structures are associated with reductions in overall brain volume and GM volumes, as well as greater lesion and black hole burden. Collectively, our results emphasize the importance of visual assessment in POMS and suggest that OCT reflects overall CNS neurodegeneration in this cohort.
Authors
- Scott N. Grossman (ORCID: https://orcid.org/0000-0001-7033-5226)
- Thibo Billiet (ORCID: https://orcid.org/0000-0002-3248-5044)
- Laura J. Balcer (ORCID: https://orcid.org/0000-0002-5136-4539)
- Lauren Krupp (ORCID: https://orcid.org/0000-0001-7003-807X)
- Anna Sosa (ORCID: https://orcid.org/0009-0008-7752-2532)
- Steven Galetta (ORCID: https://orcid.org/0000-0003-3781-7324)
- Rachel Kenney (ORCID: https://orcid.org/0000-0003-1311-5520)
- Ruben Jauregui (ORCID: https://orcid.org/0000-0002-2367-7298)
- Kimberly A. O’Neill (ORCID: https://orcid.org/0000-0001-6021-8683)
- Ugo Nwigwe (ORCID: https://orcid.org/0009-0005-6485-1386)
Institutions
- Icometrix (Belgium) (BE)
- New York University (US)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1212/nxi.0000000000200480
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00