Sex-specific association of novel complex inflammatory markers with colorectal polyps: mediating effects of triglyceride-glucose and non-high-density lipoprotein cholesterol
There were sex differences in the negative association of CALLY index with colorectal polyps, with a stronger association in women; the glucose metabolism (TyG) and lipid metabolism (Non-HDL-C) pathways partially mediated the association, and the mediating effect of TyG was more significant in women.
Authors
- Eric Yuk Fai Wan (ORCID: https://orcid.org/0000-0002-6275-1147)
- Weihong Lin (ORCID: https://orcid.org/0000-0002-7738-3949)
- Chunwu Zhang (ORCID: https://orcid.org/0000-0002-9454-306X)
- Zhonghua Wei (ORCID: https://orcid.org/0000-0001-7349-9939)
- Wenjing Gui
- Na Wang (ORCID: https://orcid.org/0000-0002-5806-4379)
- Min Li (ORCID: https://orcid.org/0000-0003-1350-9909)
- Jieru Zhou (ORCID: https://orcid.org/0000-0001-6811-8353)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1186/s12944-025-02679-3
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Wenzhou Medical University