Evaluation of diagnostic measurements in patients with non-specific complaints: A secondary analysis after implementation of a care-pathway in the emergency department

We recommend a standardized laboratory work-up for patients presenting with NSC. There is no justification for the routine use of ALAT, TSH and calcium measurements. We also recommend to incorporate bladder scans into routine care, and continuing the standardized use of ECGs, chest X-rays and urinalysis. Head CT scans, on the other hand, should be based on individualized clinical decisions. Trial number: Dutch Trial register, number NL8960.

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Publication Details

Journal
PLoS ONE
Published
2025-09-09
DOI
https://doi.org/10.1371/journal.pone.0331060
Primary Topic
Emergency and Acute Care Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of diagnostic measurements in patients with non-specific complaints: A secondary analysis after implementation of a care-pathway in the emergency department

M. A. C. Jansen, Marjolein N. T. Kremers, Marleen G. A. M. van der Velde, Harm R. Haak
PLoS ONE
Emergency and Acute Care Studies
article

Evaluation of diagnostic measurements in patients with non-specific complaints: A secondary analysis after implementation of a care-pathway in the emergency department

M. A. C. Jansen, Marjolein N. T. Kremers, Marleen G. A. M. van der Velde, Harm R. Haak
article en

Abstract

We recommend a standardized laboratory work-up for patients presenting with NSC. There is no justification for the routine use of ALAT, TSH and calcium measurements. We also recommend to incorporate bladder scans into routine care, and continuing the standardized use of ECGs, chest X-rays and urinalysis. Head CT scans, on the other hand, should be based on individualized clinical decisions. Trial number: Dutch Trial register, number NL8960.

PLoS ONEVol. 20(9)
Radboud University Nijmegen (NL), Erasmus MC (NL), Department of Health (TW), Máxima Medisch Centrum (NL), Department of Health Services (NP)
Openalex Percentile: Top 64%
Emergency and Acute Care Studies
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Evaluation of diagnostic measurements in patients with non-specific complaints: A secondary analysis after implementation of a care-pathway in the emergency department — M. A. C. Jansen, Marjolein N. T. Kremers, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS