Timing of the Arterial Switch Operation in Premature Neonates &lt; 2 kg With <scp>d</scp> -Loop Transposition of the Great Arteries and Intact Ventricular Septum—A Case Series

There is a paucity of data available regarding operative timing and approach for d-loop transposition of the great arteries (dTGA) with intact ventricular septum (IVS) in premature infants. We reviewed our surgical experience in a case series of five premature infants (<37 weeks gestational age) with dTGA/IVS and birthweights <2.0 kg. All five infants underwent primary arterial switch operation (ASO) at a median postnatal age of 19 days and weight of 1.8 kg. None of the infants had major postsurgical complications or needed reoperation. All infants were discharged home on room air. We demonstrated that premature infants <2.0 kg with dTGA/IVS can successfully undergo the ASO at <3 weeks postnatal age with no significant cardiac or neonatal complications.

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Publication Details

Journal
World Journal for Pediatric and Congenital Heart Surgery
Published
2025-09-09
DOI
https://doi.org/10.1177/21501351251361483
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Timing of the Arterial Switch Operation in Premature Neonates < 2 kg With d -Loop Transposition of the Great Arteries and Intact Ventricular Septum—A Case Series

Eleonore Valencia, Nicola Maschietto, Christopher Baird, Philip Thaler Levy et al.
World Journal for Pediatric and Congenital Heart Surgery
Congenital Heart Disease Studies
article

Timing of the Arterial Switch Operation in Premature Neonates < 2 kg With d -Loop Transposition of the Great Arteries and Intact Ventricular Septum—A Case Series

Eleonore Valencia, Nicola Maschietto, Christopher Baird, Philip Thaler Levy, Joshua W. Salvin, Francesca Sperotto, Rahul H. Rathod, Sitaram Emani, Victoria R. Bradford, Mariana Chávez, Alyssa R. Thomas
article en

Abstract

There is a paucity of data available regarding operative timing and approach for d-loop transposition of the great arteries (dTGA) with intact ventricular septum (IVS) in premature infants. We reviewed our surgical experience in a case series of five premature infants (<37 weeks gestational age) with dTGA/IVS and birthweights <2.0 kg. All five infants underwent primary arterial switch operation (ASO) at a median postnatal age of 19 days and weight of 1.8 kg. None of the infants had major postsurgical complications or needed reoperation. All infants were discharged home on room air. We demonstrated that premature infants <2.0 kg with dTGA/IVS can successfully undergo the ASO at <3 weeks postnatal age with no significant cardiac or neonatal complications.

World Journal for Pediatric and Congenital Heart SurgeryVol. 17(1)
Brigham and Women's Hospital (US), Boston Children's Hospital (US), Harvard University (US)
Openalex Percentile: Top 67%
Congenital Heart Disease Studies
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