Simultaneous optimization of multiple plans within one treatment course with dosimetric pathfinding for temporally feathered radiation therapy
A framework for the simultaneous optimization of multiple coplanar or non-coplanar sub-plans within one treatment course was developed. Simultaneous optimization was investigated with a phantom and three clinically motivated cases for TFRT planning. OAR dose modulation in the sub-plans was achieved while increasing target homogeneity and reducing OAR doses in the dose distribution of the total plans compared to the reference plans.
Authors
- Marco Stampanoni (ORCID: https://orcid.org/0000-0001-7486-6681)
- Silvan Mueller (ORCID: https://orcid.org/0000-0002-9835-4362)
- Gian Guyer (ORCID: https://orcid.org/0009-0002-8880-2069)
- Michael K. Fix (ORCID: https://orcid.org/0000-0002-3911-3403)
- Peter Manser (ORCID: https://orcid.org/0000-0003-3225-8025)
- Barbara Knäusl (ORCID: https://orcid.org/0000-0003-4031-1711)
- Jenny Bertholet
- Olgun Eliçin (ORCID: https://orcid.org/0000-0002-6996-0646)
- Jayanth R. Arnold (ORCID: https://orcid.org/0000-0003-4533-8374)
- Chengchen Zhu (ORCID: https://orcid.org/0009-0006-3506-8998)
Institutions
- University of Bern (CH)
- University Hospital of Bern (CH)
- Paul Scherrer Institute (CH)
- ETH Zurich (CH)
- Christian Doppler Laboratory for Thermoelectricity (AT)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/mp.18123
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00