Asparaginase Premedication With Hydrocortisone Decreases Hypersensitivity Reactions
Our retrospective cohort study provided preliminary evidence that the addition of hydrocortisone to a 2-drug premedication regimen of diphenhydramine and famotidine can decrease the rates of hypersensitivity reactions to IV PEG.
Authors
- Michael J. Burke (ORCID: https://orcid.org/0000-0001-6626-2773)
- Amy Pan (ORCID: https://orcid.org/0000-0002-7199-7704)
- Melodee Liegl
- Ryan Guerrettaz (ORCID: https://orcid.org/0000-0002-6180-0170)
- Megan Wegter
- Kalen McCabe
- Rebecca Volmy
Institutions
- Children's Hospital of Wisconsin (US)
- Medical College of Wisconsin (US)
- Quantitative BioSciences (US)
- European Society for Blood and Marrow Transplantation (NL)
Publication Details
- Journal
- Journal of Pediatric Hematology/Oncology
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1097/mph.0000000000003128
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00