Deer Antler S‐Adenosylmethionine Ameliorates Depression‐Like Behaviors and Neuroinflammation in <scp>CUMS</scp> Mice

SAM can improve depression-like behaviors in CUMS mice and enhance their mobility. SAM inhibits neuroinflammation and glycolysis, and also suppresses the activation of microglia.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-09-01
DOI
https://doi.org/10.1111/cns.70569
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Deer Antler S‐Adenosylmethionine Ameliorates Depression‐Like Behaviors and Neuroinflammation in CUMS Mice

Liping Zhai, Heping Shen, Genghuan Wang, Chenyang Han et al.
1 links
CNS Neuroscience & Therapeutics
Tryptophan and brain disorders
article

Deer Antler S‐Adenosylmethionine Ameliorates Depression‐Like Behaviors and Neuroinflammation in CUMS Mice

Liping Zhai, Heping Shen, Genghuan Wang, Chenyang Han, Wenyan Li, Yongjian Liu, Li Guo, Shasha Wu, Jian Rong Sheng
article en

Abstract

SAM can improve depression-like behaviors in CUMS mice and enhance their mobility. SAM inhibits neuroinflammation and glycolysis, and also suppresses the activation of microglia.

CNS Neuroscience & TherapeuticsVol. 31(9)
Dalian Medical University (CN), Jiaxing University (CN), First Affiliated Hospital of Dalian Medical University (CN)
Openalex Percentile: Top 77%
Tryptophan and brain disorders
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