Long‐term efficacy and safety of tirzepatide in participants with type 2 diabetes with inadequate glycaemic control on metformin and/or sulfonylurea: Post‐hoc analysis of <scp>SURPASS</scp> ‐4

Tirzepatide significantly improved glycaemic control and body weight reduction compared to insulin glargine over 104 weeks in participants with type 2 diabetes inadequately controlled on metformin and/or sulfonylurea. The safety profile of tirzepatide was acceptable, with a lower incidence of hypoglycaemia than insulin glargine.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-09-09
DOI
https://doi.org/10.1111/dom.70047
Citations
1
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
1.29

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article

Long‐term efficacy and safety of tirzepatide in participants with type 2 diabetes with inadequate glycaemic control on metformin and/or sulfonylurea: Post‐hoc analysis of SURPASS ‐4

Jiawei Xu, Linong Ji, Haixia Guan, Huijuan Yuan et al.
1 citations
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
1.29
article

Long‐term efficacy and safety of tirzepatide in participants with type 2 diabetes with inadequate glycaemic control on metformin and/or sulfonylurea: Post‐hoc analysis of SURPASS ‐4

Jiawei Xu, Linong Ji, Haixia Guan, Huijuan Yuan, Hongwei Jiang, Jie Sun
article en
1 citations

Abstract

Tirzepatide significantly improved glycaemic control and body weight reduction compared to insulin glargine over 104 weeks in participants with type 2 diabetes inadequately controlled on metformin and/or sulfonylurea. The safety profile of tirzepatide was acceptable, with a lower incidence of hypoglycaemia than insulin glargine.

Diabetes Obesity and MetabolismVol. 27(11)
Peking University (CN), Peking University People's Hospital (CN), Henan Provincial People's Hospital (CN), First Affiliated Hospital of Henan University of Science and Technology (CN), Guangdong Academy of Medical Sciences (CN), Lilly (China) (CN)
Eli Lilly and Company
Openalex Percentile: Top 15%
Diabetes Treatment and Management
1.29
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