Synthesis, Crystal Analyses, and Chiroptical Properties of Coumarin-Containing Helicenes
Four novel coumarin-containing arenes bearing a [5]/[6]helicene unit (<b>5</b>, <b>7</b>, <b>11</b>, and <b>13</b>) have been readily synthesized and structurally verified by X-ray crystallographic analysis. The chiral resolution of molecules <b>7</b>, <b>11</b>, and <b>13</b> has enabled a detailed investigation of their chiroptical properties and the kinetics of enantiomerization, manifesting that the [6]helicenes <b>11</b> and <b>13</b> exhibit a more enhanced chiroptical response compared to [5]helicene <b>7</b>.
Authors
- Jiawei Gao (ORCID: https://orcid.org/0000-0003-4432-1132)
- Jinchong Xiao (ORCID: https://orcid.org/0000-0002-5451-220X)
- Chengxiu Wang (ORCID: https://orcid.org/0000-0002-9583-239X)
- Ran Zhang (ORCID: https://orcid.org/0000-0003-3661-7785)
- Yanjie Zhu
- Shiyong Li (ORCID: https://orcid.org/0000-0002-3215-7278)
- Guofeng Chen (ORCID: https://orcid.org/0000-0003-3321-5932)
Institutions
- Hebei Chemical and Pharmaceutical College (CN)
- State Key Laboratory of Synthetic Chemistry (CN)
- Hebei University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1021/acs.orglett.5c03046
- Citations
- 1
- Primary Topic
- Synthesis and Properties of Aromatic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.94