Leveraging Machine Learning for Rapid and Accurate Diagnosis of Acute Leukemia

ML models based on leukocyte and CPD parameters enhance the predictability of AL detection and lineage differentiation at a pre-microscopic level. Integrating these models into hematology analyzers provides a cost-effective, novel tool for detection and differentiation. Interpretable predictions assist experts, reducing subjectivity and expediting final diagnosis through immunophenotyping and molecular studies.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2025-09-09
DOI
https://doi.org/10.1111/ijlh.14555
Primary Topic
Digital Imaging for Blood Diseases
Type
article
Field-Weighted Citation Impact
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article

Leveraging Machine Learning for Rapid and Accurate Diagnosis of Acute Leukemia

Anand Kakarla, Vandana Lal, Gurleen Oberoi, Reena Nakra et al.
International Journal of Laboratory Hematology
Digital Imaging for Blood Diseases
article

Leveraging Machine Learning for Rapid and Accurate Diagnosis of Acute Leukemia

Anand Kakarla, Vandana Lal, Gurleen Oberoi, Reena Nakra, B. Chandrasekhar, Ajay Gupta, Beulah Priscilla Maddirala
article en

Abstract

ML models based on leukocyte and CPD parameters enhance the predictability of AL detection and lineage differentiation at a pre-microscopic level. Integrating these models into hematology analyzers provides a cost-effective, novel tool for detection and differentiation. Interpretable predictions assist experts, reducing subjectivity and expediting final diagnosis through immunophenotyping and molecular studies.

International Journal of Laboratory HematologyVol. 48(1)
Rangaraya Medical College (IN), Woxsen School of Business (IN), Program for Appropriate Technology in Health (IN), CSIR National Physical Laboratory of India (IN)
Openalex Percentile: Top 77%
Digital Imaging for Blood Diseases
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