Differences in the Corneal Biomechanical Responses to LASIK and KLEx Based on Parametric Numerical Simulation

Finite element simulations indicate that KLEx may provide improved corneal stability compared to LASIK under comparable surgical conditions. However, this biomechanical advantage is not absolute and depends on multiple factors, including refractive correction magnitude, central corneal thickness, and flap or cap thickness. These findings suggest that as refractive correction increases, cap or flap thickness decreases, or central corneal thickness increases, the biomechanical differences between KLEx and LASIK diminish. In certain cases, KLEx may exhibit biomechanical risks comparable to LASIK. These results highlight the need for a personalized approach in refractive surgery planning, considering both biomechanical and surgical complexity factors.

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Publication Details

Journal
Journal of Refractive Surgery
Published
2025-09-01
DOI
https://doi.org/10.3928/1081597x-20250707-06
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Differences in the Corneal Biomechanical Responses to LASIK and KLEx Based on Parametric Numerical Simulation

Ahmed Elsheikh, XueFei Li, Shenglong Luo, Fangjun Bao et al.
Journal of Refractive Surgery
Corneal surgery and disorders
article

Differences in the Corneal Biomechanical Responses to LASIK and KLEx Based on Parametric Numerical Simulation

Ahmed Elsheikh, XueFei Li, Shenglong Luo, Fangjun Bao, GuoXin Luo, ShiHao Chen, Liang-Ying He, Fan Lü, Junjie Wang, Fan Yang, XiaoBo Zheng
article en

Abstract

Finite element simulations indicate that KLEx may provide improved corneal stability compared to LASIK under comparable surgical conditions. However, this biomechanical advantage is not absolute and depends on multiple factors, including refractive correction magnitude, central corneal thickness, and flap or cap thickness. These findings suggest that as refractive correction increases, cap or flap thickness decreases, or central corneal thickness increases, the biomechanical differences between KLEx and LASIK diminish. In certain cases, KLEx may exhibit biomechanical risks comparable to LASIK. These results highlight the need for a personalized approach in refractive surgery planning, considering both biomechanical and surgical complexity factors.

Journal of Refractive SurgeryVol. 41(9)
Moorfields Eye Hospital NHS Foundation Trust (GB), University of Liverpool (GB), Wenzhou Medical University (CN), National Institute for Health and Care Research (GB), Affiliated Eye Hospital of Wenzhou Medical College (CN), Mianyang Third People's Hospital (CN), Nanyang Institute of Technology (CN), Nanyang Medical College (CN), The First People's Hospital of Guiyang (CN), Beijing Advanced Sciences and Innovation Center (CN), University College London (GB), Beihang University (CN)
Openalex Percentile: Top 67%
Corneal surgery and disorders
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