MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting <i>CPT1A</i> and <i>ACSL4</i>
miR‑372‑3p functions as a tumor suppressor in HCC by directly downregulating <i>CPT1A</i> and <i>ACSL4</i>, thereby inhibiting FAO and disrupting lipid metabolism. Targeting this miRNA and FAO axis may offer a novel therapeutic strategy for HCC.
Authors
- Chinnatam Phetkong (ORCID: https://orcid.org/0000-0002-9721-8342)
- Chaiyaboot Ariyachet (ORCID: https://orcid.org/0000-0001-8647-7376)
- Pisit Tangkijvanich (ORCID: https://orcid.org/0000-0002-2926-8671)
- Pannathon Thamjamrassri
- Thammachanok Boonto
Institutions
- Chulalongkorn University (TH)
Publication Details
- Journal
- Bioimpacts
- Published
- 2025-08-20
- DOI
- https://doi.org/10.34172/bi.31075
- Citations
- 2
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.87