Inhibition of dipeptidyl peptidase 9 improves sorafenib sensitivity by inducing ferroptosis in hepatocellular carcinoma

Inhibition of DPP9 improves sorafenib sensitivity by promoting ferroptosis in HCC, which provides novel evidence for DPP9 as an HCC treatment target synergizing with sorafenib.

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Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2025-09-09
DOI
https://doi.org/10.1007/s00432-025-06300-z
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Inhibition of dipeptidyl peptidase 9 improves sorafenib sensitivity by inducing ferroptosis in hepatocellular carcinoma

Jun Zou, Q. Li, Yang Wang
Journal of Cancer Research and Clinical Oncology
Peptidase Inhibition and Analysis
article

Inhibition of dipeptidyl peptidase 9 improves sorafenib sensitivity by inducing ferroptosis in hepatocellular carcinoma

Jun Zou, Q. Li, Yang Wang
article en

Abstract

Inhibition of DPP9 improves sorafenib sensitivity by promoting ferroptosis in HCC, which provides novel evidence for DPP9 as an HCC treatment target synergizing with sorafenib.

Journal of Cancer Research and Clinical OncologyVol. 151(9)
Hubei University of Chinese Medicine (CN), Shandong Institute of Food and Drug Inspection (CN), ZheJiang Institute For Food and Drug Control (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 67%
Peptidase Inhibition and Analysis
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Inhibition of dipeptidyl peptidase 9 improves sorafenib sensitivity by inducing ferroptosis in hepatocellular carcinoma — Jun Zou, Q. Li, et al. · Journal of Cancer Research and Clinical Oncology (2025) | TGRS Research Map | TGRS