Quality-of-Life Outcomes in Adults and Children With Chiari 1 Malformation and in Those Managed Without Surgery: A Prospective, Multicenter, Observational Study
This study demonstrates the stability of quality-of-life domains in adults and children with CM1 after 12 months who have been managed without surgery. Further studies are required to understand the determinants of poor quality of life in patients with CM1 and to investigate interventions for improving quality of life. There is a further need for robust comparison of surgical and nonsurgical management for patients with CM1.
Authors
- Laurence Dale Watkins (ORCID: https://orcid.org/0000-0003-0678-3774)
- Rory J. Piper (ORCID: https://orcid.org/0000-0002-6422-5853)
- Ajai Chari (ORCID: https://orcid.org/0000-0003-0053-147X)
- Susan Isabel Honeyman (ORCID: https://orcid.org/0000-0002-5117-9405)
- Jayaratnam Jayamohan
- William B. Lo
- Nicholas Haden
- Matthew Alexander Boissaud-Cooke (ORCID: https://orcid.org/0000-0002-1046-6918)
- M Zubair Tahir
- Margaret Fry (ORCID: https://orcid.org/0000-0003-1265-7096)
- Shivani Rajkumar
- Linda D’Antona (ORCID: https://orcid.org/0000-0001-9918-5225)
- Rodney J. Laing (ORCID: https://orcid.org/0000-0002-0221-7225)
- Justyna O. Ekert (ORCID: https://orcid.org/0000-0002-4202-5746)
- Milo Hollingworth (ORCID: https://orcid.org/0000-0002-0669-2314)
- Edward Dyson (ORCID: https://orcid.org/0000-0002-2539-5374)
- Fardad T. Afshari
- Daniel Thompson (ORCID: https://orcid.org/0000-0002-1769-2870)
- Saeed Kayhanian (ORCID: https://orcid.org/0000-0003-1123-7890)
- Graham Flint
- Wai Cheong Soon (ORCID: https://orcid.org/0000-0001-8286-2410)
- Angelos G. Kolias (ORCID: https://orcid.org/0000-0003-3992-0587)
- Julie Woodfield (ORCID: https://orcid.org/0000-0003-3645-500X)
- Shailendra Magdum
- Harshad Sanghvi
- Michael D Cearns
Institutions
- North Bristol NHS Trust (GB)
- Nottingham University Hospitals NHS Trust (GB)
- University of Liverpool (GB)
- Queen Elizabeth Hospital Birmingham (GB)
- University Hospitals of North Midlands NHS Trust (GB)
- Great Ormond Street Hospital (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- John Radcliffe Hospital (GB)
- Royal National Orthopaedic Hospital (GB)
- Edinburgh Royal Infirmary (GB)
- Walton Centre (GB)
- Birmingham Children's Hospital (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Addenbrooke's Hospital (GB)
- Queen Elizabeth University Hospital (GB)
- University Hospitals Plymouth NHS Trust (GB)
- University College London (GB)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1227/neu.0000000000003718
- Citations
- 1
- Primary Topic
- Spinal Dysraphism and Malformations
- Type
- article
- Field-Weighted Citation Impact
- 1.88