Green Synthetic Amide‐Modified Hyper‐Cross‐Linked Adsorption Resin for Efficiently Separating Chlorogenic Acid From <i>Eucommia ulmoides</i> Extracts
Eucommia ulmoides Oliver leaf is rich in chlorogenic acid, which has antioxidant, antiviral, and anti-inflammatory activities. In this work, a new and green strategy for functional hyper-crosslinked adsorption resin based on Friedel-Crafts reaction of pendant vinyl groups in divinylbenzene with anhydrous ethanol and acrylamide grafting polymerization was developed, and the obtained HCREt-AM resin had excellent performance on chlorogenic acid separation from Eucommia ulmoides Oliver leaf extract. Adsorption isotherm and kinetics study showed the adsorption process fitted by Langmuir adsorption isotherm and pseudo-second-order kinetic equation. The dynamic saturated adsorption capacity of 88.0 mg·g<sup>-1</sup> was obtained, and chlorogenic acid content was raised from 7.91% to 48.27%. The pH-controlled ionization of chlorogenic acid determined the adsorption process, and π-π stacking, hydrophobic interactions, hydrogen bonding, and electrostatic interactions are the main adsorption mechanisms.
Authors
- Haifeng Chen (ORCID: https://orcid.org/0000-0002-7241-2149)
- Zhijie Shen
- Hailong Li (ORCID: https://orcid.org/0000-0001-5284-1897)
- Lian Xiong (ORCID: https://orcid.org/0000-0003-4101-337X)
- Hairong Chen (ORCID: https://orcid.org/0000-0002-7076-2321)
- Hairong Zhang
- Xuefang Chen (ORCID: https://orcid.org/0000-0003-0025-1427)
- Xinde Chen
- Tessafa Abrham Ashagrie
Institutions
- University of Science and Technology of China (CN)
- Guangxi University (CN)
- Shenyang University of Technology (CN)
- Guangzhou Institute of Energy Conversion (CN)
- Shenyang University of Chemical Technology (CN)
Publication Details
- Journal
- Journal of Separation Science
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/jssc.70256
- Primary Topic
- Radioactive element chemistry and processing
- Type
- article
- Field-Weighted Citation Impact
- 0.00