Are the dermatological cut-off values of commercially available ELISAs for BP180-NC16A appropriate when applied for diagnosis of oral mucous membrane pemphigoid?. Results of a preliminary study

The BP180-NC16A ELISA cutoff values designed for cutaneous BP may not be equally accurate when applied for the diagnosis of OMMP. The use of cut-off values specific for OMMP and a panel of several antigens specific for OMMP may improve the clinical utility of ELISAs; however, problems deriving from low specificity should be acknowledged.

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Publication Details

Journal
Minerva Dental and Oral Science
Published
2025-09-09
DOI
https://doi.org/10.23736/s2724-6329.25.05004-1
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
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article

Are the dermatological cut-off values of commercially available ELISAs for BP180-NC16A appropriate when applied for diagnosis of oral mucous membrane pemphigoid?. Results of a preliminary study

Andrea Gabusi, Federica Filippi, Davide Bartolomeo Gissi, Lucio Montebugnoli et al.
Minerva Dental and Oral Science
Autoimmune Bullous Skin Diseases
article

Are the dermatological cut-off values of commercially available ELISAs for BP180-NC16A appropriate when applied for diagnosis of oral mucous membrane pemphigoid?. Results of a preliminary study

Andrea Gabusi, Federica Filippi, Davide Bartolomeo Gissi, Lucio Montebugnoli, Federico Bardazzi, Camilla Loi, Cosimo Misciali
article en

Abstract

The BP180-NC16A ELISA cutoff values designed for cutaneous BP may not be equally accurate when applied for the diagnosis of OMMP. The use of cut-off values specific for OMMP and a panel of several antigens specific for OMMP may improve the clinical utility of ELISAs; however, problems deriving from low specificity should be acknowledged.

Minerva Dental and Oral ScienceVol. 74(5)
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT), University of Bologna (IT)
Openalex Percentile: Top 66%
Autoimmune Bullous Skin Diseases
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