Ibrutinib-associated hematoma of the liver: role of ultrasound in diagnosis and clinical management
Ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, has transformed the management of mantle cell lymphoma (MCL) but is associated with an elevated risk of bleeding. We report a rare case of hepatic subcapsular hematoma due to ibrutinib in a patient with relapsed MCL. Ultrasound was crucial in the early detection, monitoring, and management of this rare but potentially severe complication.
Authors
- Emilia Cappello
- Marcello Maestri (ORCID: https://orcid.org/0000-0002-5693-9151)
- Angela Di Matteo (ORCID: https://orcid.org/0000-0002-2307-1544)
- Enrico Brunetti
- Rosa Buonamassa (ORCID: https://orcid.org/0009-0001-0103-6609)
- Sofia Frattola
Institutions
- University of Pavia (IT)
- University Hospital Foundation (CA)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Journal of Ultrasound
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1007/s40477-025-01059-y
- Citations
- 2
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 3.25
Funders
- Università degli Studi di Pavia