Abnormal Amyloid-β Duration, Tau, and Neurodegeneration in Cranial Images
In this longitudinal cohort study, subtle neurodegeneration was observed soon after the onset of Aβ pathology. These results may be consistent with Aβ pathology as a pathological state.
Authors
- Tobey J. Betthauser (ORCID: https://orcid.org/0000-0001-8856-1352)
- Bradley Christian (ORCID: https://orcid.org/0000-0001-5072-3512)
- Lianlian Du
- Barbara B. Bendlin (ORCID: https://orcid.org/0000-0002-0580-9875)
- Erin M. Jonaitis (ORCID: https://orcid.org/0009-0004-5091-8255)
- Nathaniel A. Chin (ORCID: https://orcid.org/0000-0001-8008-9356)
- Carol Van Hulle
- Cynthia M. Carlsson (ORCID: https://orcid.org/0000-0001-5743-1563)
- Ozioma C. Okonkwo (ORCID: https://orcid.org/0009-0009-8764-811X)
- Sanjay Asthana (ORCID: https://orcid.org/0000-0002-3998-4479)
- Sterling C. Johnson
- Rebecca Langhough
- Henry Gilreath Stephenson
Institutions
- Rush University Medical Center (US)
- University of Wisconsin System (US)
- University of Wisconsin–Madison (US)
- University of Illinois Chicago (US)
- William S. Middleton Memorial Veterans Hospital (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.31093
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00