Teleangiectatic Osteosarcoma Treated by Surgery and Chemotherapy: A Report of 223 Affected Patients From the Cooperative Osteosarcoma Study Group ( <scp>COSS</scp> )
This large analysis proves teleangiectatic osteosarcoma to be a disease predominantly of the metaphyses of the young. While detected only rarely, the true incidence of genetic tumor predispositions would require prospective assessments. Behaving like other osteosarcoma subtypes in many other ways, this variant may show greater chemosensitivity and hence somewhat better outcomes than other subtypes.
Authors
- Leo Kager (ORCID: https://orcid.org/0000-0003-4954-6488)
- Wolf Hassenpflug (ORCID: https://orcid.org/0000-0002-4230-5828)
- Thekla von Kalle (ORCID: https://orcid.org/0000-0001-8851-5014)
- Jendrik Hardes (ORCID: https://orcid.org/0000-0002-8408-2255)
- Daniel Baumhoer (ORCID: https://orcid.org/0000-0002-2137-7507)
- Claudia Rössig (ORCID: https://orcid.org/0000-0002-8672-5285)
- Michaela Nathrath (ORCID: https://orcid.org/0000-0002-1584-1115)
- Andreas Beilken
- Markus Metzler (ORCID: https://orcid.org/0000-0002-4523-1676)
- Claudia Blattmann (ORCID: https://orcid.org/0000-0003-4045-5838)
- Stefan Bielack (ORCID: https://orcid.org/0000-0003-2144-3153)
- Andreas E. Kulozik (ORCID: https://orcid.org/0000-0003-1953-0848)
- Vanessa Mettmann (ORCID: https://orcid.org/0000-0002-4460-8830)
- Benjamin Sorg
- Godehard Friedel (ORCID: https://orcid.org/0000-0002-0340-4719)
- Stefanie Hecker‐Nolting (ORCID: https://orcid.org/0000-0002-1815-138X)
- M. Werner
- Matthias Kevric
Institutions
- University of Vienna (AT)
- University of Basel (CH)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Medizinische Hochschule Hannover (DE)
- Universitätsklinikum Erlangen (DE)
- Ruhrlandklinik (DE)
- München Klinik Schwabing (DE)
- Universitätsklinikum Tübingen (DE)
- Klinik und Poliklinik für Kinder- und Jugendmedizin (DE)
- University Hospital Münster (DE)
- Vivantes Klinikum (DE)
- Olgahospital (DE)
- Klinikum Braunschweig (DE)
- Essen University Hospital (DE)
- St Anna Children's Hospital (AT)
- Zentrum für Kinderheilkunde (DE)
- Society of Paediatric Oncology and Haematology (DE)
- Universitätsklinik für Kinder und Jugendpsychiatrie (AT)
- Klinikum Kassel (DE)
- Klinikum Stuttgart (DE)
- Chirurgische Universitätsklinik Heidelberg (DE)
- St. Anna Children's Cancer Research Institute
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/cam4.71211
- Citations
- 1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52