Clinical Significance of Circulating Tumor Cells in the Portal Vein of Patients with Hepatocellular Carcinoma Undergoing Anatomical Liver Resection
Portal vein CTCs are significant predictors of portal vein invasion, recurrence, and survival in HCC. PD-L1-positive portal vein CTCs may contribute to immune evasion and tumor progression. These findings suggest that portal vein CTCs are valuable prognostic biomarkers and potential therapeutic targets.
Authors
- Hideki Ohdan (ORCID: https://orcid.org/0000-0002-9066-1288)
- Takeshi Tadokoro (ORCID: https://orcid.org/0000-0001-6617-9750)
- Tsuyoshi Kobayashi (ORCID: https://orcid.org/0000-0001-7364-1798)
- Daisuke Takei (ORCID: https://orcid.org/0000-0002-4957-6030)
- Michinori Hamaoka (ORCID: https://orcid.org/0000-0001-8546-9876)
- Keiso Matsubara (ORCID: https://orcid.org/0000-0001-6346-0475)
- Yosuke Namba (ORCID: https://orcid.org/0000-0003-0578-9517)
- Ko Oshita (ORCID: https://orcid.org/0000-0002-3384-3800)
- Shintaro Kuroda (ORCID: https://orcid.org/0000-0001-9881-0420)
- Yuka Tanaka
Institutions
- Hiroshima University (JP)
- Shikoku Cancer Center (JP)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1245/s10434-025-18295-5
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.32