Clinically significant bradycardia in children with respiratory syncytial virus bronchiolitis receiving dexmedetomidine: effect modification by mechanical ventilation
Children with RSV bronchiolitis experienced greater heart rate reduction after DMED initiation, with a higher likelihood of clinically significant bradycardia if IMV is in use at DMED initiation or if admitted before the COVID-19 pandemic. Caution is warranted when treating RSV bronchiolitis patients with DMED.
Authors
- Rasha S. Farag (ORCID: https://orcid.org/0000-0002-2691-0032)
- Carly E. Milliren (ORCID: https://orcid.org/0000-0001-6280-8417)
- J. Brian McAlvin
- Jennifer P. Stevens (ORCID: https://orcid.org/0000-0002-9880-9662)
- Geetha Iyer (ORCID: https://orcid.org/0000-0003-1442-195X)
- Aditya S Kalluri
Institutions
- Damietta University (EG)
- Boston Children's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Ministry of Health and Population (EG)
Publication Details
- Journal
- BMJ Paediatrics Open
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1136/bmjpo-2025-003625
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00