Effects of Hypothyroidism on the Extracellular Matrix of the Vocal Folds of Adult Female Rats
Hypothyroidism was able to cause changes in the extracellular matrix of the vocal folds of female rats. We found an increase in the concentration of type I collagen and type III collagen in the animals with hypothyroidism. There was no difference in the concentration of elastin and hyaluronic acid between the hypothyroid and control groups.
Authors
- Gisele Giannocco (ORCID: https://orcid.org/0000-0002-0126-7677)
- João Roberto Maciel Martins (ORCID: https://orcid.org/0000-0002-0204-3552)
- Jônatas Bussador do Amaral (ORCID: https://orcid.org/0000-0001-5819-0474)
- Noemi Grigoletto De Biase (ORCID: https://orcid.org/0000-0002-5025-1903)
- Welber Chaves Mororó (ORCID: https://orcid.org/0000-0003-4981-3996)
- Karine V. G. de Oliveira (ORCID: https://orcid.org/0009-0001-2157-6979)
Institutions
- Universidade Federal de São Paulo (BR)
- Pontifícia Universidade Católica de São Paulo (BR)
Publication Details
- Journal
- Otolaryngology
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1002/ohn.70020
- Primary Topic
- Voice and Speech Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior