Ventral Anterior–Lateral Complex of the Thalamus Mediates Chronic Stress‐Induced Pain Hypersensitivity and Underlies Electroacupuncture Analgesia
This study reveals the pivotal role of thalamic VAL CaMKIIα-positive neurons in chronic stress-associated pain hypersensitivity and elucidates EA's analgesic mechanisms, providing novel therapeutic strategies for emotion-pain comorbidity.
Authors
- Wei Yu (ORCID: https://orcid.org/0000-0003-2610-8952)
- Peipei Feng (ORCID: https://orcid.org/0000-0002-3358-9267)
- Qing S. Li
- Zui Shen (ORCID: https://orcid.org/0000-0002-9264-203X)
- Min He (ORCID: https://orcid.org/0000-0001-7113-2973)
- Jie Chen (ORCID: https://orcid.org/0000-0002-8337-183X)
Institutions
- Tongde Hospital of Zhejiang Province (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/brb3.70855
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- National Natural Science Foundation of China
- Zhejiang Chinese Medical University
- Natural Science Foundation of Zhejiang Province