SAMCell: Generalized label-free biological cell segmentation with segment anything

Using SAMCell, biologists can quickly and automatically obtain cell segmentation results of higher quality than previous methods. Further, these results can be obtained through our custom Graphical User Interface, thus decreasing the human labor required in cell culturing.

Authors

Craig R. Forest (ORCID: https://orcid.org/0000-0001-5343-1769)
Danfei Xu (ORCID: https://orcid.org/0000-0002-8744-3861)
Eduardo A. Aponte (ORCID: https://orcid.org/0000-0001-8287-194X)
Caitlin van Zyl (ORCID: https://orcid.org/0000-0001-7776-3565)
Alexandra D. VandeLoo
Nathan J. Malta
Saahil Sanganeriya

Institutions

Georgia Institute of Technology (US)

Publication Details

Journal: PLoS ONE
Published: 2025-09-08
DOI: https://doi.org/10.1371/journal.pone.0319532
Citations: 1
Primary Topic: Cell Image Analysis Techniques
Type: article
Field-Weighted Citation Impact: 1.63

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article

SAMCell: Generalized label-free biological cell segmentation with segment anything

Craig R. Forest, Danfei Xu, Eduardo A. Aponte, Caitlin van Zyl et al.

Sep 8, 2025

1 citations

PLoS ONE

Cell Image Analysis Techniques

1.63

article

SAMCell: Generalized label-free biological cell segmentation with segment anything

Craig R. Forest, Danfei Xu, Eduardo A. Aponte, Caitlin van Zyl, Alexandra D. VandeLoo, Nathan J. Malta, Saahil Sanganeriya

September 8, 2025article en

1 citations

Abstract

Using SAMCell, biologists can quickly and automatically obtain cell segmentation results of higher quality than previous methods. Further, these results can be obtained through our custom Graphical User Interface, thus decreasing the human labor required in cell culturing.

PLoS ONEVol. 20(9)

Georgia Institute of Technology (US)

Openalex Percentile: Top 12%

Cell Image Analysis Techniques

1.63

DOI Open Access PDF OpenAlex

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SAMCell: Generalized label-free biological cell segmentation with segment anything — Craig R. Forest, Danfei Xu, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS