Geostatistical analysis to guide treatment decisions for soil-transmitted helminthiasis control in Uganda
The prevalence of STH infection has declined considerably across Uganda compared to the early 2000s. However, deworming needs remain heterogeneous across districts. Through geostatistical modeling, districts were classified according to the latest World Health Organization's (WHO) treatment guidelines. This approach optimizes treatment distribution and allows for prioritization of populations with the greatest needs. We estimated that tablet requirements are approximately 40% lower compared to the current twice-a-year deworming regimen, which contributes towards WHO's goal of halving the number of tablets required for preventive chemotherapy by 2030.
Authors
- Kristin M. Sullivan (ORCID: https://orcid.org/0000-0001-6810-4998)
- Betty Nabatte (ORCID: https://orcid.org/0000-0002-8158-4348)
- Penelope Vounatsou (ORCID: https://orcid.org/0000-0002-4904-5352)
- Prudence Beinamaryo
- Benjamin Tinkitina (ORCID: https://orcid.org/0000-0002-9572-9413)
- Alfred Mubangizi
- Paul M. Emerson (ORCID: https://orcid.org/0000-0002-6478-8816)
- Bryan O. Nyawanda (ORCID: https://orcid.org/0000-0003-0069-1473)
- Hilda Kyarisiima
- Jürg Utzinger
Institutions
- Swiss Tropical and Public Health Institute (CH)
- University of Basel (CH)
- Ministry of Health (UG)
- The Task Force for Global Health (US)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1371/journal.pntd.0013467
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00