Estimating the associations between women’s maltreatment in childhood and inflammatory biomarker levels prior to and during pregnancy
No statistically significant associations were identified between childhood maltreatment and selected inflammatory biomarkers in this sample of well-educated, primarily non-Hispanic White women. These findings should be interpreted with caution given the limited statistical power and measurement variability. Further investigation of these associations in more vulnerable populations might enhance our understanding of biological mechanisms linking maternal childhood abuse to adverse neurodevelopment in offspring.
Authors
- Adrian Medina (ORCID: https://orcid.org/0000-0002-8838-6010)
- Bohao Wu (ORCID: https://orcid.org/0000-0002-3278-196X)
- Rajarshi Mukherjee (ORCID: https://orcid.org/0000-0002-5761-8958)
- Andrea L. Roberts (ORCID: https://orcid.org/0000-0001-5023-4399)
- Natalie Slopen (ORCID: https://orcid.org/0000-0002-5644-6007)
- Chirag M. Vyas (ORCID: https://orcid.org/0000-0002-4262-2786)
- Shruthi Mahalingaiah (ORCID: https://orcid.org/0000-0002-5527-5787)
- Jorge E. Chavarro (ORCID: https://orcid.org/0000-0002-4436-9630)
- Marc G. Weisskopf (ORCID: https://orcid.org/0000-0003-4513-9834)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- McLean Hospital (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1371/journal.pone.0331905
- Primary Topic
- Child Abuse and Trauma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health