Systemic Envenomation via Ocular Route from a Neurotoxic Snake Venom Ophthalmia--A Case Report.

Snake envenomation is a neglected tropical disease with two million snake bites reported each year (WHO). Much less common is snake venom ophthalmia secondary to eye exposure from spitting snakes. This paper reports an unusual case of systemic envenomation via the ocular route of a 14-year old male from the Philippines. A mixture of snake blood and venom came in contact with the patient's left eye causing severe pain and blurring of vision, shortly followed by generalized body weakness and ptosis. Copious irrigation with normal saline was done at the emergency room, and Purified Cobra Antivenin (PCAV) was administered. Symptoms of systemic envenomation abated following PCAV administration. Ofloxacin ophthalmic drops and eye lubrication were prescribed for seven days to minimize complications, and the patient was discharged well after three days of hospitalization. Although difficult to ascertain, signs and symptoms pointed to systemic envenomation, and this could be the first case of an unconventional venom route to date. This paper opens possibilities and serves as precedent for future research - ocular envenomation, snake venom, and blood components, and symptomatic management.

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Publication Details

Journal
PubMed
Published
2025-09-01
DOI
https://doi.org/10.6705/j.jacme.202509_15(3).0005
Primary Topic
Venomous Animal Envenomation and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Systemic Envenomation via Ocular Route from a Neurotoxic Snake Venom Ophthalmia--A Case Report.

G. Rodríguez, Denilson Custodio, Christy Aleen P Sabueto, Ella Joy L Nogas
PubMed
Venomous Animal Envenomation and Studies
article

Systemic Envenomation via Ocular Route from a Neurotoxic Snake Venom Ophthalmia--A Case Report.

G. Rodríguez, Denilson Custodio, Christy Aleen P Sabueto, Ella Joy L Nogas
article en

Abstract

Snake envenomation is a neglected tropical disease with two million snake bites reported each year (WHO). Much less common is snake venom ophthalmia secondary to eye exposure from spitting snakes. This paper reports an unusual case of systemic envenomation via the ocular route of a 14-year old male from the Philippines. A mixture of snake blood and venom came in contact with the patient's left eye causing severe pain and blurring of vision, shortly followed by generalized body weakness and ptosis. Copious irrigation with normal saline was done at the emergency room, and Purified Cobra Antivenin (PCAV) was administered. Symptoms of systemic envenomation abated following PCAV administration. Ofloxacin ophthalmic drops and eye lubrication were prescribed for seven days to minimize complications, and the patient was discharged well after three days of hospitalization. Although difficult to ascertain, signs and symptoms pointed to systemic envenomation, and this could be the first case of an unconventional venom route to date. This paper opens possibilities and serves as precedent for future research - ocular envenomation, snake venom, and blood components, and symptomatic management.

PubMedVol. 15(3)
University of Southern Philippines Foundation (PH)
Openalex Percentile: Top 74%
Venomous Animal Envenomation and Studies
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