Allicin Aplealleviates Gouty Arthritis by Regulating the Gut-Joint Axis, Reducing XOD Activity, Inhibiting Oxidative Stress, and Suppressing NLRP3 Inflammasome Activation
This study highlights allicin as a promising therapeutic candidate for GA, emphasizing its potential to inhibit oxidative stress and inflammatory responses by regulating the gut-joint axis.
Authors
- Pan-miao Liu
- Meng Bian (ORCID: https://orcid.org/0000-0002-2889-3192)
- Hao Wu (ORCID: https://orcid.org/0000-0002-6713-7752)
- Jiahui Hong
- Jianjun Yang (ORCID: https://orcid.org/0000-0001-6785-9627)
- Yihong Li (ORCID: https://orcid.org/0000-0002-5476-1943)
- Manman Pang
Institutions
- National Institutes for Food and Drug Control (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/dddt.s540116
- Citations
- 2
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 2.86