Identification of Bone Metastasis-Related Gene Networks in Lung Cancer: Implications for Bone Metabolism

These findings suggest that Bayesian network analysis is a reliable machine learning approach for uncovering causal gene relationships in cancer metastasis. Furthermore, FADS1 may serve as a potential therapeutic target in lung cancer bone metastasis. The validity of this network was supported by in vitro experiments using a lung cancer cell line.

Authors

Institutions

Publication Details

Journal
Journal of Bone Metabolism
Published
2025-08-31
DOI
https://doi.org/10.11005/jbm.25.863
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Identification of Bone Metastasis-Related Gene Networks in Lung Cancer: Implications for Bone Metabolism

Junho K. Hur, Sung Bae Park, Jungwoo Kim, Seong-Ho Park
Journal of Bone Metabolism
RNA modifications and cancer
article

Identification of Bone Metastasis-Related Gene Networks in Lung Cancer: Implications for Bone Metabolism

Junho K. Hur, Sung Bae Park, Jungwoo Kim, Seong-Ho Park
article en

Abstract

These findings suggest that Bayesian network analysis is a reliable machine learning approach for uncovering causal gene relationships in cancer metastasis. Furthermore, FADS1 may serve as a potential therapeutic target in lung cancer bone metastasis. The validity of this network was supported by in vitro experiments using a lung cancer cell line.

Journal of Bone MetabolismVol. 32(3)
Seoul National University (KR), SNUH SMG-SNU Boramae Medical Center (KR), Hanyang University Medical Center (KR), Hanyang University (KR)
Openalex Percentile: Top 79%
RNA modifications and cancer
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.