Identification of Bone Metastasis-Related Gene Networks in Lung Cancer: Implications for Bone Metabolism
These findings suggest that Bayesian network analysis is a reliable machine learning approach for uncovering causal gene relationships in cancer metastasis. Furthermore, FADS1 may serve as a potential therapeutic target in lung cancer bone metastasis. The validity of this network was supported by in vitro experiments using a lung cancer cell line.
Authors
- Junho K. Hur (ORCID: https://orcid.org/0000-0003-3794-1149)
- Sung Bae Park (ORCID: https://orcid.org/0000-0002-4652-3056)
- Jungwoo Kim
- Seong-Ho Park
Institutions
- Seoul National University (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Hanyang University Medical Center (KR)
- Hanyang University (KR)
Publication Details
- Journal
- Journal of Bone Metabolism
- Published
- 2025-08-31
- DOI
- https://doi.org/10.11005/jbm.25.863
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00