UTERINE LEIOMYOMATA WITH LIVER METASTSIS: A CASE REPORT

Leiomyomas are the most common benign monoclonal neoplasm of smooth muscle cells of uterus..The incidence increases with age,4.3 per 1000woman years for 25-29 years old and 22.5 for 40-44 years old. Leiomyomata presents as abnormal uterinebleeding, pelvic pain, back pain, urinary symptoms.The different variants are: mitoticallyactive leiomyoma , cellular leiomyoma , leiomyoma with bizzare nuclei (also called atypical orsymplastic), smooth muscle tumor of uncertain malignant potential (STUMP),while the malignantvariant are the Leiomyosarcoma (LMSs). LMS arises from smooth muscle cells or from precursor mesenchymal stem cells.The peak incidence of uLMS occurs in perimenopausal age group but can also start after the thirddecade of life. About 3-7% of all uterine malignancies are uterine sarcoma and in uterine sarcomasLMS accounts for 80% .[1].