Isocitrate dehydrogenase mutation and microenvironment in gliomas: do immunotherapy approaches matter?
The reversal of the immunosuppressive effects by IDH inhibitors has opened exciting avenues for combinatorial immunotherapies such as vaccines and immune checkpoint inhibitors.
Authors
- Michael Platten (ORCID: https://orcid.org/0000-0002-4746-887X)
Institutions
- University of Mannheim (DE)
- German Cancer Research Center (DE)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Bernstein Center for Computational Neuroscience Heidelberg-Mannheim (DE)
- Helmholtz Institute Mainz (DE)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- Current Opinion in Neurology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1097/wco.0000000000001426
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00