The role of adrenal-sparing surgery in the management of aldosterone-producing adenoma: a systematic review and meta-analysis

Our systematic review underscores that LPA for treating APA has similar functional outcomes in terms of biochemical success and clinical response compared with total adrenalectomy, with fewer complications. However, given the observational nature of the currently available studies and the heterogeneity among them in the study population and surgical outcomes definitions, a clinical trial should be conducted to confirm these results.

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Publication Details

Journal
European Journal of Endocrinology
Published
2025-08-29
DOI
https://doi.org/10.1093/ejendo/lvaf180
Citations
1
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
1.29
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article

The role of adrenal-sparing surgery in the management of aldosterone-producing adenoma: a systematic review and meta-analysis

L. Zarain, Alfonso Muriel, Marta Araujo‐Castro, A. Artiles Medina et al.
1 citations
European Journal of Endocrinology
Hormonal Regulation and Hypertension
1.29
article

The role of adrenal-sparing surgery in the management of aldosterone-producing adenoma: a systematic review and meta-analysis

L. Zarain, Alfonso Muriel, Marta Araujo‐Castro, A. Artiles Medina, C. Mínguez Ojeda, Alfonso Sanjuánbenito, Felicia A. Hanzu, V. Gómez Dos Santos, Óscar Vidal, Enrique Mercader, Joaquín Gómez Ramirez
article en
1 citations

Abstract

Our systematic review underscores that LPA for treating APA has similar functional outcomes in terms of biochemical success and clinical response compared with total adrenalectomy, with fewer complications. However, given the observational nature of the currently available studies and the heterogeneity among them in the study population and surgical outcomes definitions, a clinical trial should be conducted to confirm these results.

European Journal of EndocrinologyVol. 193(3)
Instituto Cajal (ES), Hospital Universitario La Paz (ES), Hospital General Universitario Gregorio Marañón (ES), Hospital Clínic de Barcelona (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Hospital Universitario Ramón y Cajal (ES), Universitat de Barcelona (ES)
Openalex Percentile: Top 15%
Hormonal Regulation and Hypertension
1.29
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The role of adrenal-sparing surgery in the management of aldosterone-producing adenoma: a systematic review and meta-analysis — L. Zarain, Alfonso Muriel, et al. · European Journal of Endocrinology (2025) | TGRS Research Map | TGRS