Identifying Poor Responders to STN DBS in Parkinson Disease: The Role of Rapid Disease Progression in the First Year in Optimal Responders to Levodopa
Candidates for surgery with less impairment in activities of daily living may have less favourable outcomes after STN-DBS, despite an optimal response during the pre-operative Levodopa challenge. The worsening of axial symptoms due to disease progression might contribute to poorer outcomes, underscoring the need for better identification of these symptoms before surgery.
Authors
- Maurizio Zibetti (ORCID: https://orcid.org/0000-0002-2939-343X)
- Elisa Montanaro (ORCID: https://orcid.org/0000-0002-2254-9956)
- Leonardo Lopiano (ORCID: https://orcid.org/0000-0001-9098-387X)
- Francesca Morgante (ORCID: https://orcid.org/0000-0002-9834-3639)
- Mark John Edwards (ORCID: https://orcid.org/0000-0002-8283-9015)
- Carlo Alberto Artusi (ORCID: https://orcid.org/0000-0001-8579-3772)
- Lucia Ricciardi (ORCID: https://orcid.org/0000-0001-9401-3301)
- Marianna Sarchioto (ORCID: https://orcid.org/0000-0003-0877-832X)
Institutions
- St George's, University of London (GB)
- King's College London (GB)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- King's College Hospital NHS Foundation Trust (GB)
- International Neuromodulation Society (US)
- University of Turin (IT)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1111/ene.70342
- Citations
- 1
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39