Correlation of nutrition with neuropathy in ovarian cancer patients

The relationship between nutritional parameters (L3 SMI and albumin) and the incidence of chemotherapy-induced peripheral neuropathy (CIPN) in ovarian cancer patients treated with paclitaxel and carboplatin. The study included 53 patients and logistic regression identified age, height, TSH and hemoglobin levels as independent predictors of neuropathy. NCV detected subclinical neuropathy in patients without overt symptoms. We show that NCV is a valuable tool for early detection of CIPN, especially in high-risk patients and highlights the need for larger studies to explore the role of inflammatory markers in this context.

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Bioinformation
Published
2025-08-31
DOI
https://doi.org/10.6026/973206300212328
Primary Topic
Cancer Treatment and Pharmacology
Type
article
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Correlation of nutrition with neuropathy in ovarian cancer patients

Anirudh Singh, Archit Jain, Vikas Asati, Amit Jasvant Shah et al.
Bioinformation
Cancer Treatment and Pharmacology
article

Correlation of nutrition with neuropathy in ovarian cancer patients

Anirudh Singh, Archit Jain, Vikas Asati, Amit Jasvant Shah, Rajesh Patidar, Hemendra Mishra, Astha Parmar, Prakash Chitalkar
article en

Abstract

The relationship between nutritional parameters (L3 SMI and albumin) and the incidence of chemotherapy-induced peripheral neuropathy (CIPN) in ovarian cancer patients treated with paclitaxel and carboplatin. The study included 53 patients and logistic regression identified age, height, TSH and hemoglobin levels as independent predictors of neuropathy. NCV detected subclinical neuropathy in patients without overt symptoms. We show that NCV is a valuable tool for early detection of CIPN, especially in high-risk patients and highlights the need for larger studies to explore the role of inflammatory markers in this context.

BioinformationVol. 21(08)
Sri Aurobindo Institute of Medical Sciences (IN)
Openalex Percentile: Top 67%
Cancer Treatment and Pharmacology
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