Remimazolam in elderly patients undergoing EBUS-TBNA: protocol for a randomized clinical trial

This randomized trial compared remimazolam and propofol for EBUS-TBNA anesthesia in elderly patients. Remimazolam demonstrated accelerated Steward recovery and enhanced hemodynamic stability, whereas propofol exhibited risks of adipose tissue deposition and hypotension. These pharmacodynamic profiles inform anesthetic optimization in geriatric cohorts, necessitating multicenter validation of age-adjusted protocols.

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Publication Details

Journal
International Journal of Surgery Protocols
Published
2025-08-20
DOI
https://doi.org/10.1097/sp9.0000000000000058
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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0.00
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article

Remimazolam in elderly patients undergoing EBUS-TBNA: protocol for a randomized clinical trial

Maiqiao Yang, Liang He, Yali Liu, Furong Zhang et al.
International Journal of Surgery Protocols
Intensive Care Unit Cognitive Disorders
article

Remimazolam in elderly patients undergoing EBUS-TBNA: protocol for a randomized clinical trial

Maiqiao Yang, Liang He, Yali Liu, Furong Zhang, Yuqin Chen, Lihong Ma
article en

Abstract

This randomized trial compared remimazolam and propofol for EBUS-TBNA anesthesia in elderly patients. Remimazolam demonstrated accelerated Steward recovery and enhanced hemodynamic stability, whereas propofol exhibited risks of adipose tissue deposition and hypotension. These pharmacodynamic profiles inform anesthetic optimization in geriatric cohorts, necessitating multicenter validation of age-adjusted protocols.

International Journal of Surgery ProtocolsVol. 29(4)
Kunming Medical University (CN), Yan'an Hospital Affiliated To Kunming Medical University (CN)
Openalex Percentile: Top 72%
Intensive Care Unit Cognitive Disorders
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