Population Pharmacokinetic and Pharmacodynamic Modeling of Enteric-Coated Aspirin Capsule and Tablet Formulations in Healthy Subjects
This model adequately described the PK and PD of enteric-coated aspirin and demonstrated comparable TXB2 inhibition between the capsule and tablet formulations, supporting their potential interchangeability in clinical practice.
Authors
- Jae Moon Koh (ORCID: https://orcid.org/0009-0009-0725-3450)
- In‐Jin Jang (ORCID: https://orcid.org/0000-0002-8384-3139)
- Kyung‐Sang Yu (ORCID: https://orcid.org/0000-0003-0921-7225)
- Juyoung Khwarg (ORCID: https://orcid.org/0000-0001-7097-2006)
- Soyoung Lee (ORCID: https://orcid.org/0000-0001-5799-4489)
- SeungHwan Lee (ORCID: https://orcid.org/0000-0002-1713-9194)
Institutions
- Chungnam National University (KR)
- Seoul National University Hospital (KR)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/dddt.s533428
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chungnam National University
- Daewoong Pharmaceutical Company