Targeted Viral Delivery to Corticospinal Neurons in a Neonatal Rat to Study Spinal Cord Injury

Source: Smit, R. D., et al. Targeting the Corticospinal Tract in Neonatal Rats with a Double-Viral Vector using Combined Brain and Spine Surgery. J. Vis. Exp. (2021)This video demonstrates the targeted delivery of viral vectors to corticospinal neurons in a neonatal rat. The protocol enables precise gene expression using anterograde and retrograde viral injections, facilitating research on neural regeneration and plasticity following spinal cord injury.

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Publication Details

Journal: Journal of Visualized Experiments
Published: 2025-08-29
DOI: https://doi.org/10.3791/23835
Primary Topic: Neonatal and fetal brain pathology
Type: article
Field-Weighted Citation Impact: 0.00

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article

Targeted Viral Delivery to Corticospinal Neurons in a Neonatal Rat to Study Spinal Cord Injury

TODO TODO

Aug 29, 2025

Journal of Visualized Experiments

Neonatal and fetal brain pathology

article

Targeted Viral Delivery to Corticospinal Neurons in a Neonatal Rat to Study Spinal Cord Injury

TODO TODO

August 29, 2025article en

Abstract

Journal of Visualized Experiments

Openalex Percentile: Top 66%

Neonatal and fetal brain pathology

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Targeted Viral Delivery to Corticospinal Neurons in a Neonatal Rat to Study Spinal Cord Injury — TODO TODO · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS