Injecting Self-Assembling Peptides and Neural Precursor Cells for Spinal Cord Repair in a Rat Model

Source: Zweckberger, K., et al. Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury. J. Vis. Exp. (2015).This protocol demonstrates a targeted injection approach for spinal cord injury repair in a rat model. It involves delivering self-assembling peptides (SAPs) into the lesion core to create a supportive scaffold, followed by neural precursor cell (NPC) injections around the lesion to remodel the tissue.

Authors

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-08-29
DOI
https://doi.org/10.3791/23876
Primary Topic
Nerve injury and regeneration
Type
article
Field-Weighted Citation Impact
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article

Injecting Self-Assembling Peptides and Neural Precursor Cells for Spinal Cord Repair in a Rat Model

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Journal of Visualized Experiments
Nerve injury and regeneration
article

Injecting Self-Assembling Peptides and Neural Precursor Cells for Spinal Cord Repair in a Rat Model

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article en

Abstract

Source: Zweckberger, K., et al. Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury. J. Vis. Exp. (2015).This protocol demonstrates a targeted injection approach for spinal cord injury repair in a rat model. It involves delivering self-assembling peptides (SAPs) into the lesion core to create a supportive scaffold, followed by neural precursor cell (NPC) injections around the lesion to remodel the tissue.

Journal of Visualized Experiments
Openalex Percentile: Top 75%
Nerve injury and regeneration
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